Breakthroughs Blog

Breakthroughs brings you stories of bright ideas and bold innovations in global health.

The Latest
Emily Conron
How the partial government shutdown is affecting global health, R&D

As the partial government shutdown stretches into a fifth week – the longest in United States history – news of its impact on agencies essential to global health broadly, and research and development in particular, is taking clearer shape.

Recent

TPP: What does it mean for global health and what’s next?

After ten years of debate, on November 5, 2015, international negotiators released the final text of the largest regional trade agreement in history—the Trans Pacific Partnership (TPP).

GHTC
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Scaling up solutions to save every preemie

Preterm birth complications are the leading cause of death for children under five years of age.

GHTC
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PATH/Eric Becker
Research Roundup: Targeting cattle to fight sleeping sickness, antibodies that protect against distantly related viruses, and more

A new study suggests that the use of anti-parasitic drugs and insecticides in cattle can reduce human cases of Trypanosomiasis (sleeping sickness) by as much as 90 percent.

GHTC
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Research Roundup: tapeworm tumors, a new HIV/AIDS prevention method, and a TB test for low-resource settings

A recently released clinical report from the US Centers for Disease Control and Prevention details a case of a Colombian man who developed cancerous tumors on his lungs and liver that were comprised of tapeworm cells, rather than human cells.

GHTC
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Rapid diagnostics needed to curb antibiotic resistance

New rapid diagnostics are urgently needed to prevent unnecessary use of antibiotics and curb the growing problem of antimicrobial resistance, according to a new report from the United Kingdom’s Review on Antimicrobial Resistance (AMR).

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CDC/Prof Woodridge Foster, Prof. Frank H. Collins
Research Roundup: repurposing ivermectin to fight malaria, LED lights against dengue fever, rapid diagnostics to slow antimicrobial resistance, and more

Findings of a study presented at the American Society of Tropical Medicine and Hygiene Annual Meeting last week suggest that ivermectin—a drug long used to treat river blindness and elephantiasis—can combat malaria when used in mass drug administration programs.

GHTC
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PATH/Jennifer Fox
Germany announces second PDP funding round: What’s different and how does it impact global health R&D

Earlier this month, Germany’s Federal Ministry of Education and Research (BMBF) the renewal of the German funding program for product development partnerships (PDPs) conducting research and development (R&D) for health technologies to combat poverty-related and neglected diseases (PRNDs).

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CDC/National Institute of Allergy and Infectious Diseases
Research Roundup: an aerosol TB vaccine, a new coating for HIV/AIDS drugs, drug-resistant malaria, and more

Researchers at Tulane University successfully tested an experimental aerosol tuberculosis (TB) vaccine in monkeys, demonstrating that the candidate was more effective in protecting against infection than BCG—the only TB vaccine on the market.

GHTC
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GHTC
GHTC briefing highlights importance of health innovation to achieving global goals

With the Sustainable Development Goals (SDGs) freshly adopted, the Global Health Technologies Coalition (GHTC) gathered representatives from the private, public, and nonprofit sectors on Capitol Hill this past Wednesday to discuss what it will take to achieve the global goals.

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The R&D agenda and how it addresses access to vaccines

In this guest post, Dr. Jayasree K. Iyer—Chief Scientific Officer at the Access to Medicine Foundation—writes about the findings from their newest study, which examines the current state of the vaccine pipeline and how large pharmaceutical companies are considering access to these products.

Access to Medicine Foundation
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CDC/Dr. Scott Smith
Research Roundup: an HIV/AIDS vaccine candidate, inflatable incubator for premature babies, and US government R&D

Dr. Robert Gallo co-discovered the HIV virus and subsequently led the development of the first HIV/AIDS blood test.

GHTC
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Tackling hidden hunger through innovation

When most people think of hunger, they think of a lack of food—a nation suffering from crop failure and famine, or a family that can’t afford to put enough food on the table.

GHTC
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CDC
Research Roundup: TB R&D, malaria in pregnancy, and treatments for filarial diseases

A new briefing paper from the Infectious Diseases Society of America Center for Global Health Policy explores the state of tuberculosis (TB) research and development (R&D) including challenges for products currently in the pipeline and gaps in TB research.

GHTC
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Why we need research to detect, prevent, and ultimately, eliminate parasitic diseases

In this guest post, Dr. Monica Parise—deputy director for program and science—and Dr. Larry Slutsker—director of the Division of Parasitic Disease and Malaria—at the US Centers for Disease Control and Prevention (CDC) Center for Global Health—discuss the role of research in advancing efforts to detect, prevent, and eliminate parasitic diseases.

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Research Roundup: genetic protection against malaria, the vaccine pipeline, and counterfeit drugs and the FDA

A new study conducted by the Malaria Genomic Epidemiology Network (MalariaGEN)—a community of researchers across malaria-endemic regions—reveals a formerly unknown genetic variations that make people less susceptible to malaria.

GHTC
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PATH/Evelyn Hockstin
Research Roundup: a promising Ebola treatment, access to drugs for NCDs, a new approach to treating a deadly bacterium, and the perception of breakthrough drugs

The US Department of Health and Human Services (HHS) is partnering with New York–based Regeneron Pharmaceuticals, Inc. for the development of an Ebola treatment.

GHTC
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PATH/James Gathaney
Research Roundup: antibiotic and reproductive health R&D, leadership at the FDA, and a potential new strain of dengue fever.

The US Department of Health and Human Services (HHS) announced last week a partnership with pharmaceutical company AstraZeneca for the research and development (R&D) of antibiotics.

GHTC
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PATH/Patrick McKern
Female condoms: the feel and shape of things to come

Take a stroll through any pharmacy and you’ll see shelves stacked with male condoms of many varieties, but look for a female condom and you aren't likely to find one for sale.

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Advocacy and partnerships for HIV/AIDS prevention for women: A post from Durban, South Africa

Sitting halfway around the world from my office in Washington, DC, looking out my Durban hotel window at the Indian Ocean, I am reminded just how small and interconnected our world really is.

GHTC
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Research Roundup: HIV/AIDS self-testing and advances in dengue fever and sleeping sickness R&D

A new study suggests that with basic training, individuals can learn to accurately and safely test themselves for HIV/AIDS.

GHTC
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