April 11, 2023
G20 nations must bolster global R&D capabilities to confront urgent health challenges
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PATH/Francesa Holme
As the G20 Health Working Group meets next week to consider political commitments to better prepare for future health threats and advance health equity, GHTC urges them to prioritize the following actions to bolster global research and development (R&D) capabilities:
- Support the creation of a new pandemic global medical countermeasures platform: The COVID-19 pandemic has made clear that the world needs a global, end-to-end coordination platform to facilitate the rapid development, manufacturing, and equitable delivery of medical countermeasures during health crises. G20 nations should commit to supporting and financing a new platform that builds on lessons learned from the Access to Tools Accelerator and prioritizes accountability, transparency, agility, and inclusivity in its approach.
- Fully fund the World Bank Pandemic Fund. To date, the fund has secured just US$1.6 billion in pledges against its $10.5 annual target. G20 leaders should also ensure the fund invests in projects to strengthen laboratory, clinical research, and regulatory capacity to advance the development of and access to health technologies, work that is complementary to that of other international health initiatives.
- Increase investment in R&D for poverty-related and neglected diseases (PRNDs). The pandemic has diverted critical resources and attention away from battles against longstanding global health challenges like HIV/AIDS, malaria, tuberculosis, and neglected tropical diseases. To reinvigorate these fights, G20 nations should boost funding and incentives for PRND R&D and support product development partnerships, which are uniquely equipped to advance technologies that are affordable, accessible, and adapted to the communities who need them.
- Center the needs of women, children, and other vulnerable populations in R&D. This includes enacting policies to improve collection and analysis of sex- and gender-disaggregated data and to ensure adequate representation of women, pregnant and lactating individuals, and other underrepresented populations in clinical trials. G20 nations should also work with the World Health Organization to develop target product profiles to advance therapeutic formulations for children, pregnant individuals, and other at-risk populations.
- Reprioritize R&D to combat antimicrobial resistance (AMR). The G20 has demonstrated past leadership on AMR research through its support of the Global AMR R&D Hub. G20 nations should build on this by continuing to support hub operations and increasing investments and incentives for R&D for new and improved antimicrobials, point-of-care diagnostic devices, vaccines, and other technologies required to stay ahead of this rising threat.
- Integrate R&D into pandemic prevention, preparedness, and response mechanisms. As negotiations continue on the pandemic accord and reforms to the International Health Regulations (IHR), G20 nations should push for the accord to embrace a holistic approach to supporting end-to-end product development and for the IHR to include new amendments to promote R&D coordination and genetic sequence sharing and new indicators to assess R&D capabilities at the country level.
It is our hope that the commitments of this year’s G20 will chart a new path toward realizing a more resilient, fit-for-purpose, and equitable R&D ecosystem.
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